Histiocytoma is a common benign skin tumor that arises from Langerhans cells, a type of immune cell found in the skin. It is most frequently seen in young dogs under 3 years of age, although it can occur at any age or breed
Histiocytomas develop due to localized proliferation of epidermal dendritic cells (Langerhans cells)
They are considered reactive or benign proliferations rather than true neoplasms and often spontaneously regress as the immune system mounts a response
The dog was presented with a rapidly growing skin 2 nodules located near the left tarsal joint. The owner reported a bite wound at the same site approximately one year earlier, which had healed completely following routine wound care.
Recently, a small raised masses appeared at the same location and enlarged over two weeks. The lesions was non-painful and non-pruritic, but the dog occasionally licked the area. No systemic illness was noted.
Due to the location near the joint, where friction and trauma could delay regression or cause ulceration, surgical excision
The mass was completely excised with clean margins, and Sample submitted to lab
Microscopic evaluation confirmed a proliferation of Langerhans-type round cells in the dermis, forming a dense cellular mass.
The cells exhibited abundant pale cytoplasm, round nuclei, and minimal atypia.
No invasion into surrounding tissues was observed.
Findings were consistent with Atypical (Deep )histiocytoma.
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